Thcnm

O-Methyl-Δ⁹-tetrahydrocannabinol (O-Methyl-Δ⁹-THC) is a derivative of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive compound in cannabis. This synthetic analog is part of a broader category of THC derivatives that have been studied for their pharmacological properties.

Key Features:
1. Chemical Structure:
O-Methyl-Δ⁹-THC is structurally similar to Δ⁹-THC but has a methyl group (-CH₃) added to the oxygen atom of the phenolic hydroxyl group. This modification can alter its binding affinity to cannabinoid receptors and its metabolic stability.
2. Pharmacology:
Like Δ⁹-THC, O-Methyl-Δ⁹-THC likely interacts with cannabinoid receptors CB1 and CB2 in the endocannabinoid system. The methylation can increase lipophilicity, potentially enhancing blood-brain barrier penetration, and may result in a different potency or duration of effects compared to Δ⁹-THC.
3. Psychoactive Effects:
While less studied, O-Methyl-Δ⁹-THC is expected to have psychoactive properties similar to Δ⁹-THC, given its structural resemblance. The exact potency, subjective effects, and safety profile depend on its interaction with cannabinoid receptors and metabolism in the body.
4. Research and Applications:
• O-Methyl-Δ⁹-THC has been of interest in medicinal chemistry for studying structure-activity relationships (SARs) of cannabinoids.
• It is not commonly found in natural cannabis and is typically synthesized in a laboratory setting.
• Research on its therapeutic potential or use as a recreational drug is limited compared to Δ⁹-THC.
5. Legal Status:
Due to its similarity to Δ⁹-THC, it may be classified as a controlled substance in many jurisdictions, depending on local analog laws. Its status would depend on its intended use and how it is regulated under local drug laws.

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